With three major GLP-1 class compounds now in widespread use, a common question is: do they all require the same storage? Here's a breakdown of each compound's stability and storage requirements.
Semaglutide (Ozempic / Wegovy / compounded)
Well-studied stability profile. Lyophilized: stable at room temp 1-3 months. Reconstituted: refrigerate, use within 28-30 days. Most forgiving of the three for short-term room temperature exposure.
Tirzepatide (Mounjaro / Zepbound / compounded)
Similar stability to semaglutide. As a dual GLP-1/GIP agonist it has a slightly more complex molecular structure, but storage requirements are essentially the same. Refrigerate reconstituted vials, use within 28-30 days.
Retatrutide (compounded, investigational)
As a triple agonist (GLP-1, GIP, glucagon), retatrutide is the most complex molecule of the three. Lyophilized retatrutide should be stored refrigerated when possible — room temperature stability data is less established than semaglutide. Once reconstituted, refrigerate and use within 28 days. Extra caution is warranted given the higher cost and limited availability of retatrutide.
The Storage Bottom Line
All three compounds benefit from the same core protection: hard-shell physical protection, light blocking, and refrigeration after reconstitution. A VialLock case handles the physical and light protection whether you're using semaglutide, tirzepatide, or retatrutide. Shop VialLock cases.